221 N Main Street

Excellent Opportunity to own your own building in Historic Downtown Hannibal. North Main Street attracts visitors and locals to shops, restaurants, and most of all the Mark Twain Boyhood Home and Museum properties. 221 North Main has had a substantial rehab around 2010. Storefront restoration, new mechanical systems, roofing, interior remake, and lighting. Second floor has potential for additional retail square footage. 3 HVAC units, side entry off Bird Street and includes two private concrete parking pads. Over 4000 square feet of finished space. Be apart of Hannibal’s tourist community.

Listing Courtesy of Prestige Realty, Inc. Based on information submitted to the MLS GRID as of Wednesday, May 20th, 2026 at 10:35:03 PM. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.
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