219 N Main Street

A rare find in Historic Downtown Hannibal is available for a new business venture. 219 N. Main was built in 1858 by J.B. Brown for a drug store, this drug store continured until 1986. Main floor is a walk back in time with original cabinets and wood floors and tin ceilings. Second & third floors have been converted into loft living. Fully equipped kitchen, luxurious bath, and an open floor plan on 3rd floor offers Mississippi River views. Second floor has served as an artist’s work space but also has Air B&B possibilities. Updates include 2 hi-efficiency HVAC units, 2-200 amp service, metal roof, two story deck overlooking courtyard. One block south of Mark Twain’s Boyhood Home.

Listing Courtesy of Prestige Realty, Inc. Based on information submitted to the MLS GRID as of Thursday, June 5th, 2025 at 08:16:24 PM. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.
Data services provided by IDX Broker